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Sigurdís Haraldsdóttir - Prófessor

Sigurdís Haraldsdóttir

–

Heilbrigðisvísindasvið

Sigurdís Haraldsdóttir

Prófessor

Aðsetur
LSH - Hringbraut
Tölvupóstur
sigurdis [hjá] hi.is

Starfseining
Læknadeild

ORCID vefsíða
https://orcid.org/0000-0002-5050-3699
Rannsóknagátt – Sigurdís Haraldsdóttir

Show Útgefið efni

2025

Effects of aspirin at diagnosis on the survival of colorectal cancer patientsScandinavian Journal of Gastroenterology
Lynch syndrome screening in colorectal and endometrial cancers in IcelandActa Oncologica

2023

Large Cancer Pedigree Involving Multiple Cancer Genes including Likely Digenic MSH2 and MSH6 Lynch Syndrome (LS) and an Instance of Recombinational Rescue from LSCancers
Metachronous Colorectal Cancer in Icelandic MSH6 and PMS2 Lynch Syndrome Carriers in 1955-2017Gastroenterology

2022

Germline Testing for Individuals with Pancreatic Adenocarcinoma and Novel Genetic Risk FactorsHematology/Oncology Clinics of North America
Universal tumor screening in a population with MSH6- and PMS2-associated Lynch syndromeGenetics in Medicine

2021

Implementing Systematic Genetic Counseling and Multigene Germline Testing for Individuals With Pancreatic CancerJCO Oncology Practice
Implementation of a cloud-based electronic patient-reported outcome (ePRO) platform in patients with advanced cancerJournal of Patient-Reported Outcomes
Profiling diverse sequence tandem repeats in colorectal cancer reveals co-occurrence of microsatellite and chromosomal instability involving Chromosome 8Genome Medicine
Mismatch Repair (MMR) Gene Alteration and BRAF V600E Mutation Are Potential Predictive Biomarkers of Immune Checkpoint Inhibitors in MMR-Deficient Colorectal CancerOncologist
Universal Screening of Gastrointestinal Malignancies for Mismatch Repair Deficiency at StanfordJNCI Cancer Spectrum
A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT)The Lancet Oncology

2020

An amino-terminal BRAF deletion accounting for acquired resistance to RAF/EGFR inhibition in colorectal cancerCold Spring Harbor molecular case studies
Germline testing for patients with BRCA1/2 mutations on somatic tumor testingJNCI Cancer Spectrum
Immune-Related Adverse Events and Immune Checkpoint Inhibitor Efficacy in Patients with Gastrointestinal Cancer with Food and Drug Administration-Approved Indications for ImmunotherapyOncologist

2019

Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndromeBMJ Open Gastroenterology
Clinical characteristics of patients with colorectal cancer with double somatic mismatch repair mutations compared with Lynch syndromeJournal of Medical Genetics
Microsatellite instability and adjuvant chemotherapy in stage II colon cancerAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Genetic/Familial high-risk assessmentJNCCN Journal of the National Comprehensive Cancer Network
Comparison of definitive chemoradiation with 5-fluorouracil versus capecitabine in anal cancerJournal of Gastrointestinal Oncology

2018

Promising New Agents for Colorectal CancerCurrent Treatment Options in Oncology
Targeting BRAF mutations in high-grade neuroendocrine carcinoma of the colonJNCCN Journal of the National Comprehensive Cancer Network
The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomyScandinavian Journal of Gastroenterology
Histology of colorectal adenocarcinoma with double somatic mismatch-repair mutations is indistinguishable from those caused by Lynch syndromeHuman Pathology
Phenotypes of organ involvement in sarcoidosisEuropean Respiratory Journal
Phase I trial of dabrafenib and pazopanib in BRAF mutated advanced malignanciesJCO Precision Oncology
Management of Borderline Resectable Pancreatic CancerInternational Journal of Radiation Oncology Biology Physics
Tumor Molecular Testing Guides Anti-PD-1 Therapy and Provides Evidence for Pathogenicity of Mismatch Repair VariantsOncologist

2017

Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2Nature Communications
Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2.Nature Communications
Microsatellite instability testing using next-generation sequencing data and therapy implicationsJCO Precision Oncology
Conversion Therapy for Initially Borderline/Unresectable Metastases in Colon CancerCurrent Colorectal Cancer Reports

2016

Frequent PIK3CA Mutations in Colorectal and Endometrial Tumors With 2 or More Somatic Mutations in Mismatch Repair GenesGastroenterology
Radiation recall dermatitis with concomitant dabrafenib and pazopanib therapyJAMA Dermatology
Potential Approaches to Chemotherapy of Thyroid Cancer
Chemotherapy for Anaplastic Thyroid Cancer
Medullary Carcinoma of the Thyroid: Chemotherapy
Chemotherapy of Thyroid Cancer: General Principles
Mismatch repair deficiency concordance between primary colorectal cancer and corresponding metastasisFamilial Cancer
Discordant mismatch repair protein immunoreactivity in lynch syndrome-associated neoplasmsAmerican Journal of Clinical Pathology
Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognosesGenetics in Medicine

2015

Circulating tumor markers in patients with neuroendocrine tumors-a clinical perspectiveInternational Journal of Endocrine Oncology

2014

Colon and endometrial cancers with mismatch repair deficiency can arise from somatic, rather than germline, mutationsGastroenterology
New era for treatment in differentiated thyroid cancerThe Lancet
Krabbamein í ristli og endaþarmiLæknablaðið
Krabbamein í ristli og endaþarmiLæknablaðið
An update on clinical trials of targeted therapies in thyroid cancerCurrent Opinion in Oncology
Prostate cancer incidence in males with Lynch syndromeGenetics in Medicine
Colorectal cancer – reviewLæknablaðið
How Can Next-Generation Sequencing (Genomics) Help Us in Treating Colorectal Cancer?Current Colorectal Cancer Reports

2013

Case of sorafenib-induced thyroid stormJournal of Clinical Oncology
What is the optimal neo-adjuvant treatment for liver metastasis?Therapeutic Advances in Medical Oncology
Integrating anti-EGFR therapies in metastatic colorectal cancerJournal of Gastrointestinal Oncology

2012

A single institutional experience with panitumumab in metastatic colorectal cancer.Journal of Cancer Therapy

2010

Diagnostic accuracy of 64-slice multidetector CT for detection of in-stent restenosis in an unselected, consecutive patient populationEuropean Journal of Radiology

2009

Clinical evaluation and stress test have limited value in the diagnosis of in-stent restenosisScandinavian Cardiovascular Journal

2008

Greiningarhæfni 64 sneiǒa ölvusneiǒ myndatækniLaeknabladid
Greiningarhæfni 64 sneiða tölvusneiðmyndatækni til samanburðar við hefðbundna kransæðaþræðinguLæknablaðið

2004

Anti-proliferative effects of lichen-derived lipoxygenase inhibitors on twelve human cancer cell lines of different tissue origin in vitroPlanta Medica

2002

Effects of tenuiorin and methyl orsellinate from the lichen Peltigera leucophlebia on 5-/15-lipoxygenases and proliferation of malignant cell lines in vitroPhytomedicine

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