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Forsíða

Forsíða

Þór Eysteinsson - Professor

Þór Eysteinsson

–

Heilbrigðisvísindasvið

Þór Eysteinsson

Professor

Professor of neurophysiology

Location
Læknagarður
Phone
525 - 4887
Email
thoreys [at] hi.is

Unit
Department of Physiology

ORCID site
https://orcid.org/0000-0002-9748-5854
Research portal – Þór Eysteinsson
Under construction throughout the autumn semester 2023

Published works

2023

Progressive Cone-Rod Dystrophy and RPE Dysfunction in Mitfmi/+ MiceGenes
Membrane Permeability Is Required for the Vasodilatory Effect of Carbonic Anhydrase Inhibitors in Porcine Retinal ArteriesInternational Journal of Molecular Sciences

2022

Vasodilation of Pre-contracted Porcine Retinal Arteries by Carbonic Anhydrase Inhibitors with Enhanced LipophilicityCurrent Eye Research
Mouse microphthalmia‐associated transcription factor (Mitf) mutations affect the structure of the retinal vasculatureActa Ophthalmologica

2021

Molecular genetics of inherited retinal degenerations in Icelandic patientsClinical Genetics

2020

Mitf Links Neuronal Activity and Long-Term Homeostatic Intrinsic Plasticityeneuro
Mechanisms of Ion Transport Across the Mouse Retinal Pigment Epithelium Measured In VitroInvestigative Opthalmology & Visual Science

2019

Retinal oximetry: Metabolic imaging for diseases of the retina and brainProgress in Retinal and Eye Research
Carbonic Anhydrase Inhibitors of Different Structures Dilate Pre-Contracted Porcine Retinal ArteriesInternational Journal of Molecular Sciences
The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye functionScientific Reports

2018

Health Benefits of Walking in Nature: A Randomized Controlled Study Under Conditions of Real-Life StressEnvironment and Behavior

2017

Retinal A(2A) and A(3) adenosine receptors modulate the components of the rat electroretinogramVisual Neuroscience
Retinal Oximetry Discovers Novel Biomarkers in Retinal and Brain Diseases.Investigative ophthalmology & visual science

2016

OUTDOOR EXERCISE IS ASSOCIATED WITH BETTER CELL AGING PROFILESInternational Journal of Behavioral Medicine
Mutations in the Mitf gene affect autophagy in mouse primary RPE cells.Investigative Ophthalmology & Visual Science
Normal limits of retinal oximetry and retinal venous oxygen saturation in atrophic diseasesInvestigative Ophthalmology & Visual Science
Green exercise is associated with better cell ageing profilesEuropean Journal of Public Health
Localization of AT1 and MAS receptors on porcine retinal arteriesInvestigative Ophthalmology & Visual Science
Membrane permeable but not impermeable carbonic anhydrase inhibitors dilate precontracted porcine retinal arteriesInvestigative Ophthalmology & Visual Science

2015

Is metabolic imaging a new tool to monitor progression in retinal degenerations and atrophy?Acta Ophthalmologica
Image Quality Affects Measurements of Retinal Vessel Oxygen SaturationInvestigative Ophthalmology & Visual Science
Stimulation or blockage of the retinal A(1) adenosine receptors modifies the components of the rat electroretinogramInvestigative Ophthalmology & Visual Science

2014

The role of Cl- channels in ion transport across the apical and basolateral sides of the mouse retinal pigment epitheliumActa Ophthalmologica
Retinal vessel oxygen saturation and vessel diameter in retinitis pigmentosaActa Ophthalmologica

2013

Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptorFaseb Journal
Ion transport across the murine retinal pigment epitheliumFaseb Journal

2011

P2X(7) receptor stimulation raises lysosomal pH and triggers cytokine release from RPE cellsFaseb Journal

2010

Rapid cytokine release following stimulation of the P2X7 receptor on RPE cellsPurinergic Signalling
The A(3) adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cellsNeurochemistry International
A novel truncating mutation in VLGR1 gene, causing Usher syndrome type II and may also contribute to non-syndromic retinitis pigmentosaActa Ophthalmologica

2009

Glaucoma Filtration Surgery and Retinal Oxygen SaturationInvestigative Ophthalmology & Visual Science
Oxygen Saturation in Human Retinal Vessels Is Higher in Dark Than in LightInvestigative Ophthalmology & Visual Science
GABA agonists fail to protect the retina from ischemia-reperfusion injuryExperimental Eye Research
Dorzolamide-timolol combination and retinal vessel oxygen saturation in patients with glaucoma or ocular hypertensionBritish Journal of Ophthalmology

2007

Sveinsson chorioretinal atrophy: the mildest changes are located in the photoreceptor outer segment/retinal pigment epithelium junctionActa Ophthalmologica Scandinavica

2006

Automatic retinal oximetryInvestigative Ophthalmology & Visual Science
Optic nerve pH and PO2: the effects of carbonic anhydrase inhibition, and metabolic and respiratory acidosisActa Ophthalmologica Scandinavica

2005

Epidemiology of the optic nerve grey crescent in the Reykjavik Eye StudyBritish Journal of Ophthalmology
Carbonic anhydrase inhibition increases retinal oxygen tension and dilates retinal vesselsGraefes Archive For Clinical and Experimental Ophthalmology
Optic nerve hypoxia results from indomethacin, but not from other anti-inflammatory drugsInvestigative Ophthalmology & Visual Science
Relationships between ocular dimensions and adult stature among participants in the Reykjavik Eye StudyActa Ophthalmologica Scandinavica
Automatic retinal oximetryInvestigative Ophthalmology & Visual Science
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administrationJournal of Controlled Release
Optic nerve oxygenationProgress in Retinal and Eye Research
Visual function in helicoid peripapillary chorioretinal degeneration(HPCD)/Sveinsson's chorioretinal atrophy (SCRA) as assessed by microperimetryInvestigative Ophthalmology & Visual Science

2004

Dorzolamide induces vasodilatation in isolated pre-contracted bovine retinal arteriesExperimental Eye Research
Automatic selection of measurement points in multispectral fundus images for retinal oximetryInvestigative Ophthalmology & Visual Science
Spectrophotometric retinal oximetry of retinal arterioles and venules.Investigative Ophthalmology & Visual Science
Indomethacin lowers optic nerve oxygen tension and reduces the effect of carbonic anhydrase inhibition and carbon dioxide breathingBritish Journal of Ophthalmology
Optic nerve oxygen tension: the effects of timolol and dorzolamideBritish Journal of Ophthalmology
Electroretinographic assessment of retinal function in microphthalmia mutant miceExperimental Eye Research

2003

Optic nerve oxygen tension: The effect of indomethacinInvestigative Ophthalmology & Visual Science
Optic nerve oxygen tension: The effect of timolol and dorzolamideInvestigative Ophthalmology & Visual Science
Modulation of the components of the rat dark-adapted electroretinogram by the three subtypes of GABA receptorsVisual Neuroscience
Carbonic anhydrase inhibitors elevate optic nerve oxygen tension in pigs by blocking intracellular CA IIInvestigative Ophthalmology & Visual Science

2002

Optic nerve oxygen tension is not affected by a metabolic acidosisInvestigative Ophthalmology & Visual Science
Central corneal thickness, radius of the corneal curvature and intraocular pressure in normal subjects using non-contact techniques: Reykjavik Eye StudyActa Ophthalmologica Scandinavica
Effect of a carbonic anhydrase inhibitor on contractile activity in retinal arteriesFaseb Journal
Retinal and optic nerve oxygen tension and carbonic anhydrase inhibition in pigsInvestigative Ophthalmology & Visual Science
Non-invasive retinal oxymetry in normal human subjectsInvestigative Ophthalmology & Visual Science

2001

Interocular luminance differences have differential effects on the pattern reversal visual evoked potential in amblyopia.Investigative Ophthalmology & Visual Science
The effect of intravenous administration of carbonic anhydrase inhibitors and NH4Cl on pre-optic nerve pH in pigs.Investigative Ophthalmology & Visual Science
Ocular implants and movements of the artificial eye.Investigative Ophthalmology & Visual Science

2000

Modification of the Xenopus electroretinogram by actions of glycine in the proximal retinal.Investigative Ophthalmology & Visual Science
Optic nerve oxygen tension: effects of intraocular pressure and dorzolamideBritish Journal of Ophthalmology
Interocular luminance differences and the binocular pattern onset-offset visual evoked potential.Investigative Ophthalmology & Visual Science
Central corneal thickness, corneal curvature and intraocullar pressure in normal subjects: Reykjavik eye study.Investigative Ophthalmology & Visual Science
Epidemiology of the optic nerve gray crescent in the Reykjavik eye study.Investigative Ophthalmology & Visual Science
Modification of the Xenopus electroretinogram by actions of glycine in the proximal retinaActa Physiologica Scandinavica
The oscillatory potentials and the b-wave of the rat ERG are modified by different GABA receptor subtypes.Investigative Ophthalmology & Visual Science

1999

Optic nerve oxygen tension in pigs and the effect of carbonic anhydrase inhibitorsInvestigative Ophthalmology & Visual Science
Topical dorzolamide increases optic nerve oxygen tension in the pigInvestigative Ophthalmology & Visual Science
Optic nerve oxygen tension. The effect of intraocular pressure and carbonic anhydrase inhibition.Investigative Ophthalmology & Visual Science

1998

Helicoidal peripapillary chorioretinal degeneration: electrophysiology and psychophysics in 17 patientsBritish Journal of Ophthalmology
Helicoid Peripapillary Chorioretinal Degeneration Atrophia Areata: phenotypic variation and fine mapping of it's gene on chromosome 11p15European Journal of Human Genetics

1997

The role of GABA in modulating the Xenopus electroretinogramVisual Neuroscience

1996

The relative influence of binocular summation and tonic interocular suppression in spatial ind temporal visionInvestigative Ophthalmology & Visual Science

1995

LIGHT ADAPTATION OF THE CONE SYSTEM ELECTRORETINOGRAM IN DICHROMATS AND ANOMALOUS TRICHROMATSInvestigative Ophthalmology & Visual Science

1994

TOPICAL ACETAZOLAMIDE IN 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN (HP-BETA-CD) EYE DROPS LOWERS INTRAOCULAR-PRESSURE IN HUMANSInvestigative Ophthalmology & Visual Science
HELICOIDAL PERIPAPILLARY CHORIORETINAL DEGENERATION IN ICELAND - ELECTROPHYSIOLOGICAL FINDINGSInvestigative Ophthalmology & Visual Science
DIFFERENTIAL INFLUENCE OF SEROTONIN IN INNER VERSUS OUTER VERTEBRATE RETINAInvestigative Ophthalmology & Visual Science

1993

TONIC INTEROCULAR SUPPRESSION, BINOCULAR SUMMATION, AND THE VISUAL-EVOKED POTENTIALInvestigative Ophthalmology & Visual Science
GABAERGIC AND NON-GABAERGIC FORMS OF SUPPRESSIVE RODCONE INTERACTION (SRCI)Investigative Ophthalmology & Visual Science
ALPHA-AMINO PIMELIC ACID - ANOTHER NEW TOOL FOR RETINAL RESEARCHInvestigative Ophthalmology & Visual Science

1991

TEMPORAL AND SPATIAL PROPERTIES OF SUPPRESSIVE ROD-CONE INTERACTIONInvestigative Ophthalmology & Visual Science
TEMPORAL VARIATIONS IN THE IONIC TRANSPORT ACROSS RABBIT RETINAL-PIGMENT EPITHELIUMCurrent Eye Research
TONIC INTEROCULAR SUPPRESSION AND BINOCULAR SUMMATION IN HUMAN VISIONJournal of Physiology-London
TONIC INTEROCULAR SUPPRESSION FROM A DARK-ADAPTED EYE UPON CONTRALATERAL SPATIAL VISION - A UNIQUE TYPE OF ROD-CONE INTERACTIONInvestigative Ophthalmology & Visual Science

1989

SPATIAL AND TEMPORAL LIMITATIONS OF SUPPRESSIVE ROD-CONE INTERACTION IN XENOPUS H-CELLSJournal of Physiology-London
PHYSIOLOGICAL AND PHARMACOLOGIC ANALYSIS OF SUPPRESSIVE ROD-CONE IN NECTURUS RETINAJournal of Neurophysiology

1988

THE CELLULAR BASIS FOR SUPPRESSIVE ROD CONE INTERACTIONVisual Neuroscience

1987

SUPPRESSIVE ROD-CONE INTERACTION IN DISTAL VERTEBRATE RETINA - INTRACELLULAR RECORDS FROM XENOPUS AND NECTURUSJournal of Neurophysiology

Keywords for Specialisation:

Electrophysiology

Neurophysiology

Sensory neurobiology