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Forsíða

Stefanía P Bjarnarson - Associate Professor

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Heilbrigðisvísindasvið

Stefanía P Bjarnarson

Associate Professor

Email
spb [at] hi.is

Unit
Faculty of Medicine

Published works

2023

The adjuvants dmLT and mmCT enhance humoral immune responses to a pneumococcal conjugate vaccine after both parenteral or mucosal immunization of neonatal miceThe adjuvants dmLT and mmCT enhance humoral immune responses to a pneumococcal conjugate vaccine after both parenteral or mucosal immunization of neonatal mice

2022

A comparative study of adjuvants effects on neonatal plasma cell survival niche in bone marrow and persistence of humoral immune responsesA comparative study of adjuvants effects on neonatal plasma cell survival niche in bone marrow and persistence of humoral immune responses

2020

Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM 197 conjugate vaccineProceedings of the National Academy of Sciences
LT-K63 Enhances B Cell Activation and Survival Factors in Neonatal Mice That Translates Into Long-Lived Humoral ImmunityFrontiers in Immunology

2019

Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal MiceFrontiers in Immunology

2018

Natural killer cells play an essential role in resolution of antigen-induced inflammation in miceMolecular Immunology

2013

Pneumococcal Polysaccharide Abrogates Conjugate-Induced Germinal Center Reaction and Depletes Antibody Secreting Cell Pool, Causing HyporesponsivenessPLoS ONE

2012

Hyporesponsiveness following booster immunization with bacterial polysaccharides is caused by apoptosis of memory B cellsJournal of Infectious Diseases
The adjuvant LT-K63 can restore delayed maturation of follicular dendritic cells and poor persistence of both protein- and polysaccharide-specific antibody-secreting cells in neonatal miceJournal of Immunology

2011

Concomitant administration of Mycobacterium bovis BCG with the meningococcal C conjugate vaccine to neonatal mice enhances antibody response and protective efficacyClinical and Vaccine Immunology
Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potentialNature Communications

2009

Clara cell protein 16 (CC16) serum levels in infants during respiratory syncytial virus infectionActa Paediatrica, International Journal of Paediatrics

2008

Neonatal immune response and serum bactericidal activity induced by a meningococcal conjugate vaccine is enhanced by LT-K63 and CpG2006Vaccine

2006

Early life T Cell responses to pneumucoccal conjugates increase with age and determine the polysaccharide-specific antibody response and protective efficacyEuropean Journal of Immunology

2005

Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like responseJournal of Allergy and Clinical Immunology
The advantage of mucosal immunization for polysaccharide-specific memory responses in early lifeEuropean Journal of Immunology

2002

Intranasal immunization with pneumococcal conjugate vaccines with LT-K63, a nontoxic mutant of heat-labile enterotoxin, as adjuvant rapidly induces protective immunity against lethal pneumococcal infections in neonatal miceInfection and Immunity

Keywords for Specialisation:

Neonatal immune system

Immunological adjuvants

Neonatal immunization