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Forsíða

Sveinbjörn Gizurarson - Professor

Sveinbjörn Gizurarson

–

Heilbrigðisvísindasvið

Sveinbjörn Gizurarson

Professor

Professor

Location
Hagi
Phone
525 - 5807 8980318
Email
sveinbj [at] hi.is

Unit
Faculty of Pharmaceutical Sciences
Website
http://www.uni.hi.is/sveinbj

Published works

2024

Compliance and illiteracy when treating tuberculosisInternational Health

2023

Colour of Medicines and Children’s Acceptability? A Systematic Literature Review of Children’s Perceptions about Colours of Oral Dosage FormsPharmaceutics
Estimation of Pediatric Dosage of Antimalarial Drugs, Using Pharmacokinetic and Physiological ApproachPharmaceutics

2021

Effect of Doxycycline Microencapsulation on Buccal Films: Stability, Mucoadhesion and In Vitro Drug ReleaseGels
The effect of trehalose, antioxidants, and acetate buffer concentration on oxytocin stabilityJournal of Peptide Science
Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and ImmunomodulationPharmaceutics
Pharmacokinetics of single and repeated oral doses of esomeprazole and gastrin elevation in healthy males and femalesScandinavian Journal of Gastroenterology
Endothelium-Derived Hyperpolarizing Factor (EDHF) Mediates Acetylsalicylic Acid (Aspirin) Vasodilation of Pregnant Rat Mesenteric ArteriesInternational Journal of Molecular Sciences

2020

Modulation of immune responses using adjuvants to facilitate therapeutic vaccinationImmunological Reviews

2019

Placental protein 13 (PP13) stimulates rat uterine vessels after slow subcutaneous administration

International Journal of Women's Health
Stability of thromboxane in blood samples

Vascular Health and Risk Management
Galectin 13 (PP13) Facilitates Remodeling and Structural Stabilization of Maternal Vessels during PregnancyInternational Journal of Molecular Sciences
Aspirin causes endothelium-dependent vasodilation of resistance arteries from non-gravid and gravid ratsPregnancy Hypertension

2018

Evaluation of intranasal delivery route of drug administration for brain targetingBrain Research Bulletin

2017

Nose-to-brain transport of imatinib mesylate: A pharmacokinetic evaluationEuropean Journal of Pharmaceutical Sciences

2016

Study of Gender Differences in Proton Pump Inhibitor Dose Requirements for GERD: A Double-Blind Randomized Trial.
Placental Protein 13 Administration to Pregnant Rats Lowers Blood Pressure and Augments Fetal Growth and Venous Remodeling.

2015

The effect of cilia and the mucociliary clearance on successful drug delivery.
The Effect of Cilia and the Mucociliary Clearance on Successful Drug DeliveryBiological & Pharmaceutical Bulletin
Medical technology education for pharmacy students and practicing pharmacists in the Nordic and Baltic countriesInternational Journal of Clinical Pharmacy

2014

Placental Protein 13 (PP13) - a placental immunoregulatory galectin protecting pregnancyFrontiers in Immunology
Impact of changes to reimbursement of fixed combinations of inhaled corticosteroids and long-acting beta(2)-agonists in obstructive lung diseases: a population-based, observational studyInternational Journal of Clinical Practice
PLACENTAL PROTEIN 13: CHARACTERIZATION OF A NATURALLY OCCURRING VARIANT LACKING THE CARBOHYDRATE RECOGNITION DOMAINPlacenta
The Role of the Carbohydrate Recognition Domain of Placental Protein 13 (PP13) in Pregnancy Evaluated with Recombinant PP13 and the DelT(221) PP13 VariantPlos One
PLACENTAL PROTEIN 13 (PP13) SHOWS BENEFICIAL EFFECTS ON THE MATERNAL VASCULATURE IN PREGNANT RATS: POTENTIAL BENEFITS IN PREECLAMPSIA AND IUGRPlacenta

2013

Serum leptin concentrations, leptin mRNA expression, and food intake during the estrous cycle in rats.Laboratory animal research
In vitro evaluation of pulmonary deposition of airborne volcanic ashAtmospheric Environment
Effects of Placental Protein 13 on the Cardiovascular System in Gravid and Non-Gravid RodentsFetal Diagnosis and Therapy
Placental protein 13 (PP13): a new biological target shifting individualized risk assessment to personalized drug design combating pre-eclampsiaHuman Reproduction Update
Potential negative consequences of non-consented switch of inhaled medications and devices in asthma patientsInternational Journal of Clinical Practice

2012

Clinical consequences following regulatory changes in respect to reimbursement of statins cost by the Icelandic Social Insurance AdministrationScandinavian Journal of Public Health
Anatomical and Histological Factors Affecting Intranasal Drug and Vaccine DeliveryCurrent Drug Delivery
Anatomical and histological factors affecting intranasal drug and vaccine delivery.

2011

Did the Fall of the Icelandic Banks Affect Psychotropic Drug Use in the Population?Pharmacoepidemiology and Drug Safety

2007

Mucosal tolerance to KLH reduces BSA-induced arthritis in rats - An indication of bystander suppressionJournal of Clinical Immunology
Immunization prevents DDT buildup in mouse tissuesInternational Immunopharmacology

2006

Mucosal tolerance to KLH reduces BSA-induced arthritis in rats - an indication of bystander suppressionScandinavian Journal of Rheumatology
Influence of passive cigarette smoke on joint swelling and on mucosal tolerance induction in BSA-induced arthritisScandinavian Journal of Rheumatology
Two intranasal administration techniques give two different pharmacokinetic resultsScandinavian Journal of Laboratory Animal Science

2005

RhinoVax (R) is an efficient adjuvant in oral immunisation of young chickens and cholera toxin B is an effective oral primer in subcutaneous immunisation with Freund's incomplete adjuvantIn Vivo
Induction of protective and specific antibodies against cocaine by intranasal immunisation using a glyceride adjuvantBiological & Pharmaceutical Bulletin
Mucosal tolerance to KLH reduces BSA-induced arthritis in rats? an indication of bystander suppressionImmunology

2004

Improving unbiased left/right training of rats and use of physostigmine to counteract scopolamine-induced short-term memory impairmentScandinavian Journal of Laboratory Animal Science

2002

Intranasal bioavailability of diazepam in sheep correlated to rabbit and manInternational Journal of Pharmaceutics

2001

Electroencephalographic effects and serum concentrations after intranasal and intravenous administration of diazepam to healthy volunteersBritish Journal of Clinical Pharmacology
Serum amyloid P component inhibits influenza A virus infections: in vitro and in vivo studiesAntiviral Research

2000

Intranasal absorption of buprenorphine - in vivo bioavailability study in sheepInternational Journal of Pharmaceutics

1999

Single- and repeated-dose local toxicity in the nasal cavity of rabbits after intranasal administration of different glycols for formulations containing benzodiazepinesJournal of Pharmacy and Pharmacology
Intranasal administration of diazepam aiming at the treatment of acute seizures: clinical trials in healthy volunteers.
Intranasal immunization with pneumococcal polysaccharide conjugate vaccines protects mice against invasive pneumococcal infections.
Intranasal immunization with pneumococcal polysaccharide conjugate vaccines protects mice against invasive pneumococcal infectionsInfection and Immunity
Intranasal administration of diazepam aiming at the treatment of acute seizures: Clinical trials in healthy volunteersBiological & Pharmaceutical Bulletin

1998

Intranasal vaccination: pharmaceutical evaluation of the vaccine delivery system and immunokinetic characteristics of the immune responses.Pharmaceutical development and technology
Clinically relevant vaccine-vaccine interactions - A guide for practitionersBiodrugs
Selective augmentation of antibodies in various mucosal regions, after intranasal immunization with diphtheria in miceJournal of Pharmaceutical Sciences

1997

Pharmacokinetic and pharmacodynamic response after intranasal administration of diazepam to rabbitsJournal of Pharmacy and Pharmacology
Pharmacokinetic and pharmacodynamic response after intranasal administration of diazepam to rabbits.
Olfactory absorption of insulin to the brainDrug Delivery
Intranasal booster vaccination against diphtheria and tetanus in manVaccine
Solubilization of various benzodiazepines for intranasal administration, a pilot study.Pharmaceutical development and technology
Selective delivery of insulin into the brain: Intraolfactory absorption (vol 140, pg 77, 1996)International Journal of Pharmaceutics

1996

Selective delivery of insulin into the brain: Intraolfactory absorptionInternational Journal of Pharmaceutics
Optimal delivery of vaccines: clinical pharmacokinetic considerations.
Evaluation of local toxicity after repeated intranasal vaccination of guinea-pigsToxicology
Optimal delivery of vaccines - Clinical pharmacokinetic considerationsClinical Pharmacokinetics
Intranasal administration of insulin to rabbits using glycofurol as an absorption promoterInternational Journal of Pharmaceutics

1995

INTRANASAL ADMINISTRATION OF DIPHTHERIA TOXOID - SELECTING ANTIBODY ISOTYPES USING FORMULATIONS HAVING VARIOUS LIPOPHILIC CHARACTERISTICSVaccine

1993

INSULIN AND DIDECANOYL-L-ALPHA-PHOSPHATIDYLCHOLINE - INVITRO STUDY OF THE TRANSPORT THROUGH RABBIT NASAL MUCOSAL TISSUEInternational Journal of Pharmaceutics
THE RELEVANCE OF NASAL PHYSIOLOGY TO THE DESIGN OF DRUG ABSORPTION STUDIESAdvanced Drug Delivery Reviews

1992

STIMULATION OF THE TRANSEPITHELIAL FLUX OF INFLUENZA HA VACCINE BY CHOLERA-TOXIN B-SUBUNITVaccine
THE VIABILITY OF ISOLATED RABBIT NASAL-MUCOSA IN THE USSING CHAMBER, AND THE PERMEABILITY OF INSULIN ACROSS THE MEMBRANEInternational Journal of Pharmaceutics

1991

Insulin-carrying microspheres, in vitro studies.
THE EFFECT OF CHOLERA-TOXIN AND CHOLERA TOXIN-B SUBUNIT ON THE NASAL MUCOSAL MEMBRANEVaccine
Study of nasal enzyme activity towards insulin. In vitro.
STUDY OF NASAL ENZYME-ACTIVITY TOWARDS INSULIN - INVITROChemical & Pharmaceutical Bulletin
Estimating tissue permeability and other bioelectrical parameters using membrane voltage and short-circuit current.
INTRANASAL ADMINISTRATION OF INSULIN TO HUMANSDiabetes Research and Clinical Practice
ESTIMATING TISSUE PERMEABILITY AND OTHER BIOELECTRICAL PARAMETERS USING MEMBRANE VOLTAGE AND SHORT-CIRCUIT CURRENTChemical & Pharmaceutical Bulletin
PHARMACOKINETICS OF INTRANASAL DRUG ADMINISTRATION - THE INFLUENCE OF SOME BIOLOGICAL FACTORSJournal of Pharmaceutical Sciences
INSULIN-CARRYING MICROSPHERES, INVITRO STUDIESChemical & Pharmaceutical Bulletin

1990

ANIMAL-MODELS FOR INTRANASAL DRUG DELIVERY STUDIES - A REVIEW ARTICLEActa Pharmaceutica Nordica
Animal models for intranasal drug delivery studies. A review article.
THE INFLUENCE OF INSULIN AND SOME EXCIPIENTS USED IN NASAL INSULIN PREPARATIONS ON MUCOCILIARY CLEARANCEInternational Journal of Pharmaceutics

1989

A SIMPLE FLOW-INJECTION ANALYSIS FOR STUDIES OF DRUG-PROTEIN BINDING INTERACTIONS IN SERUMActa Pharmaceutica Nordica
A simple flow injection analysis for studies of drug-protein binding interactions in serum.
A SIMPLE FLOW-INJECTION METHOD FOR THE DETERMINATION OF BLOOD-GLUCOSE USING A TECHNICON IMMOBILIZED ENZYME COILJournal of Automatic Chemistry

1988

ACTIVATED CARBON FOR THE REMOVAL OF THE OINTMENT BASE BEFORE KINETIC ASSAY OF NITROGLYCERIN OINTMENTFresenius Zeitschrift Fur Analytische Chemie

Keywords for Specialisation:

Laboratory safety etc

Nasal drug delivery

Immunological adjuvants

Drug interactions

Drugs in pregnancy and lactation

Fetus drug delivery