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Sigurbjörg Þorsteinsdóttir - Ónæmisfræðingur

Sigurbjörg Þorsteinsdóttir

–

Stofnanir

Sigurbjörg Þorsteinsdóttir

Ónæmisfræðingur

Aðsetur
Tilraunastöð HÍ. í meinafræði - Keldum
Sími
5855117 8635470
Tölvupóstur
sibbath [hjá] hi.is

Starfseining
Tilraunastöð HÍ í meinafræði að Keldum
Vefsíða
http://keldur.is/sumarexemsrannsoknir_0

ORCID vefsíða
https://orcid.org/0000-0002-3195-4937

Útgefið efni

2018

Barley produced Culicoides allergens are suitable for monitoring the immune response of horses immunized with E-coli expressed allergensVeterinary Immunology and Immunopathology
A prospective study on insect bite hypersensitivity in horses exported from Iceland into Switzerland.Acta veterinaria Scandinavica
Longitudinal analysis of allergen-specific IgE and IgG subclasses as potential predictors of insect bite hypersensitivity following first exposure to Culicoides in Icelandic horsesVeterinary Dermatology

2017

Oral administration of transgenic barley expressing a Culicoides allergen induces specific antibody responseEquine Veterinary Journal
Neonatal Immunization with a Single IL-4/Antigen Dose Induces Increased Antibody Responses after Challenge Infection with Equine Herpesvirus Type 1 (EHV-1) at Weanling AgePlos One

2016

A preventive immunization approach against insect bite hypersensitivity: Intralymphatic injection with recombinant allergens in Alum or Alum and monophosphoryl lipid AVeterinary Immunology and Immunopathology
Establishment and characterization of fetal equine kidney and lung cells with extended lifespan. Susceptibility to equine gammaherpesvirus infection and transfection efficiencyIn Vitro Cellular & Developmental Biology-Animal

2015

Developing a preventive immunization approach against insect bite hypersensitivity using recombinant allergens: A pilot studyVeterinary Immunology and Immunopathology
Antibody and cellular immune responses of naive mares to repeated vaccination with an inactivated equine herpesvirus vaccineVaccine
Vaccination of horses against insect bite hypersensitivity: intralymphatic injection with allergens in alum or alum and monophosphoryl lipid AAllergy

2014

Insect bite hypersensitivity of horses: induction of a specific antibody response in horses after oral treatment with transgenic barley grain expressing an insect allergenAllergy

2012

Generation of equine TSLP-specific antibodies and their use for detection of TSLP produced by equine keratinocytes and leukocytes.Veterinary immunology and immunopathology
Genetic diversity of equine gammaherpesviruses (γ-EHV) and isolation of a syncytium forming EHV-2 strain from a horse in Iceland.Research in veterinary science

2010

Isolation and partial sequencing of Equid herpesvirus 5 from a horse in Iceland.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Skin-infiltrating T cells and cytokine expression in Icelandic horses affected with insect bite hypersensitivity: a possible role for regulatory T cells.Veterinary immunology and immunopathology
Selective cloning, characterization, and production of the Culicoides nubeculosus salivary gland allergen repertoire associated with equine insect bite hypersensitivity.Veterinary immunology and immunopathology

2009

Immune response against equine gammaherpesvirus in Icelandic horses.Veterinary microbiology
Insect bite hypersensitivity in the horse: comparison of IgE-binding proteins in salivary gland extracts from Simulium vittatum and Culicoides nubeculosus.Veterinary immunology and immunopathology
Cloning of IgE-binding proteins from Simulium vittatum and their potential significance as allergens for equine insect bite hypersensitivity.Veterinary immunology and immunopathology
Increased IL-4 and decreased regulatory cytokine production following relocation of Icelandic horses from a high to low endoparasite environment.Veterinary immunology and immunopathology
Identification and isolation of cDNA clones encoding the abundant secreted proteins in the saliva proteome of Culicoides nubeculosus.Insect molecular biology

2008

Study of equid herpesviruses 2 and 5 in Iceland with a type-specific polymerase chain reaction.Research in veterinary science
Mucosal immunization against ovine lentivirus using PEI-DNA complexes and modified vaccinia Ankara encoding the gag and/or env genes.Vaccine
Mutational analysis of a principal neutralization domain of visna/maedi virus envelope glycoprotein.The Journal of general virology
Systemic DNA immunization against ovine lentivirus using particle-mediated epidermal delivery and modified vaccinia Ankara encoding the gag and/or env genes.Vaccine
In vitro analysis of expression vectors for DNA vaccination of horses: the effect of a Kozak sequence.Acta veterinaria Scandinavica
Report of the 3rd Havemeyer workshop on allergic diseases of the Horse, Hólar, Iceland, June 2007.Veterinary immunology and immunopathology

2007

Immune response to maedi-visna virus.Frontiers in bioscience : a journal and virtual library
Vaccination of sheep with Maedi-visna virus gag gene and protein, beneficial or harmful?Vaccine

2006

Equine insect bite hypersensitivity: immunoblot analysis of IgE and IgG subclass responses to Culicoides nubeculosus salivary gland extract.Veterinary immunology and immunopathology
Production of monoclonal antibodies specific for native equine IgE and their application to monitor total serum IgE responses in Icelandic and non-Icelandic horses with insect bite dermal hypersensitivity.Veterinary immunology and immunopathology
Evaluation of an in vitro sulphidoleukotriene release test for diagnosis of insect bite hypersensitivity in horses.Equine veterinary journal

2005

Mucosal vaccination with an attenuated maedi-visna virus clone.Vaccine
Simultaneous mutations in CA and Vif of Maedi-Visna virus cause attenuated replication in macrophages and reduced infectivity in vivo.Journal of virology
Diagnostic tests for small ruminant lentiviruses.Veterinary microbiology

2004

Cloning and sequencing of a cDNA expressing a ribosomal P0 peptide from Culicoides nubeculosus (Diptera).Veterinary immunology and immunopathology
Transmission of small ruminant lentiviruses.Veterinary microbiology
The vif gene of maedi-visna virus is essential for infectivity in vivo and in vitro.Virology

2003

Intratracheal inoculation as an efficient route of experimental infection with maedi-visna virus.Research in veterinary science

1999

Naturally occurring mutations within 39 amino acids in the envelope glycoprotein of maedi-visna virus alter the neutralization phenotype.Journal of virology

1998

Treatment of visna virus infection in lambs with the acyclic nucleoside phosphonate analogue 9-(2-phosphonylmethoxyethyl)adenine (PMEA).Antiviral chemistry & chemotherapy
Visna virus dUTPase is dispensable for neuropathogenicity.Journal of virology
Immune response to recombinant visna virus Gag and Env precursor proteins synthesized in insect cells.Virus research
Visna in sheep as a model for chemotherapy of lentiviral central nervous system infections.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Biological and genetic differences between lung- and brain-derived isolates of maedi-visna virus.Virus genes
Constitutive and visna virus induced expression of class I and II major histocompatibility complex antigens in the central nervous system of sheep and their role in the pathogenesis of visna lesions.Neuropathology and applied neurobiology

1997

In vivo and in vitro infection with two different molecular clones of visna virus.Virology

1996

Mimicry of a 21.5 kDa myelin basic protein peptide by a Maedi Visna virus polymerase peptide does not contribute to the pathogenesis of encephalitis in sheep.Veterinary immunology and immunopathology

1995

Inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine on visna virus infection in lambs: a model for in vivo testing of candidate anti-human immunodeficiency virus drugs.Proceedings of the National Academy of Sciences of the United States of America

1994

Pathogenesis of central nervous system lesions in visna cell-mediated immunity and lymphocyte subsets in blood, brain, and cerebrospinal fluid.Annals of the New York Academy of Sciences
The effect of cyclosporin A on visna infection in sheep.Annals of the New York Academy of Sciences

1993

Antigen processing and presentation by EBV-carrying cell lines: cell-phenotype dependence and influence of the EBV-encoded LMP1.International journal of cancer
Over-expression of C-myc increases the sensitivity of Epstein-Barr virus immortalized lymphoblastoid cells to non-MHC-restricted cytotoxicity.International journal of cancer

1992

Pathogenesis of central nervous system lesions in visna: cell-mediated immunity and lymphocyte subsets in blood, brain and cerebrospinal fluid.Journal of neuroimmunology

1991

Search for the critical characteristics of phenotypically different B cell lines, Burkitt lymphoma cells and lymphoblastoid cell lines, which determine differences in their functional interaction with allogeneic lymphocytes.Cancer immunology, immunotherapy : CII
Stimulation with allogeneic Epstein-Barr virus-transformed lymphoblastoid cell lines generates HLA class I-specific CTLs with different target cell avidity.Cellular immunology
Human and ovine lentiviral infections compared.Comparative immunology, microbiology and infectious diseases

1989

Allele-specific down-regulation of MHC class I antigens in Burkitt lymphoma lines.Cellular immunology
Studies of sublines selected for loss of HLA expression from an EBV-transformed lymphoblastoid cell line. Changes in sensitivity to cytotoxic T cells activated by allostimulation and natural killer cells activated by IFN or IL-2.Journal of immunology (Baltimore, Md. : 1950)
Reversion of tumorigenicity and decreased agarose clonability after EBV conversion of an IgH/myc translocation-carrying BL line.International journal of cancer

1988

Combined treatment with interferon (IFN)-gamma and tumor necrosis factor (TNF)-alpha up-regulates the expression of HLA class I determinants in Burkitt lymphoma lines.Cellular immunology
Differential expression of HLA antigens on human B-cell lines of normal and malignant origin: a consequence of immune surveillance or a phenotypic vestige of the progenitor cells?International journal of cancer

1987

Paired Epstein-Barr virus (EBV)-negative and EBV-converted Burkitt lymphoma lines: stimulatory capacity in allogeneic mixed lymphocyte cultures.International journal of cancer
Activation of B lymphocytes by Epstein-Barr virus/CR2 receptor interaction.European journal of immunology
Allo-restricted cytotoxicity recognizing EBV-determined antigens. Comments.The Journal of molecular and cellular immunology : JMCI

1986

Differentiation-dependent sensitivity of human B-cell-derived lines to major histocompatibility complex-restricted T-cell cytotoxicity.Proceedings of the National Academy of Sciences of the United States of America
Different sensitivity of B cell lines derived from Burkitt lymphoma (BL) and normal cells (LCL) to cytotoxic T cell clones generated by autologous and allogeneic stimulation.Journal of immunogenetics
Differential recognition of tumor-derived and in vitro Epstein-Barr virus-transformed B-cell lines by fetal calf serum-specific T4-positive cytotoxic T-lymphocyte clones.Cellular immunology

1985

Selective inhibitory effect of Hu-IFN-gamma on the agarose clonability of tumor-derived lymphoid cell lines.Cellular immunology

1984

Phorbol esters inhibit the functional activation of cytotoxic precursors in mixed lymphocyte cultures.Journal of immunology (Baltimore, Md. : 1950)
T lymphocyte culture established by repeated stimulation with the autologous lymphoblastoid line. MHC class II restricted interactions with B blasts.Molecular biology & medicine
Natural killer cell sensitivity of human lymphoid lines of B-cell origin does not correlate with tumorigenicity or with the expression of certain differentiation markers.Cellular immunology

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