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Háskóli Íslands

Háskóli Íslands

Forsíða

Forsíða

Helgi Jónsson - Prófessor

Helgi Jónsson

–

Heilbrigðisvísindasvið

Helgi Jónsson

Prófessor

Prófessor í gigtarlækningum

Aðsetur
LSH - Fossvogi
Sími
5431000
Tölvupóstur
helgi [hjá] hi.is

Starfseining
Læknadeild

ORCID vefsíða
https://orcid.org/0000-0003-0187-8985

Útgefið efni

2019

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fracturesNature Communications
Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik StudyPLOS ONE
Hand and knee osteoarthritis are associated with reduced diameters in retinal vessels: the AGES-Reykjavik studyRheumatology International
2018 update of the EULAR recommendations for the management of hand osteoarthritisAnnals of the Rheumatic Diseases
Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures (Nature Communications, (2019), 10, 1, (2054), 10.1038/s41467-019-09860-0)Nature Communications

2018

Biological treatment in ankylosing spondylitis in the Nordic countries during 2010–2016: a collaboration between five biological registriesScandinavian Journal of Rheumatology
Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritisNature Genetics
Gout - a treatable condition,Þvagsýrugigt - læknanleg liðbólgaLaeknabladid
Following the genetic clues towards treatment of hand OANature Reviews Rheumatology
Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritisNature Genetics

2017

Long-Term Hormone Replacement Therapy Is Associated with Low Coronary Artery Calcium Levels in a Cohort of Older Women: The Age, Gene/Environment Susceptibility—Reykjavik StudyJournal of the American Geriatrics Society
Age related prevalence of hand osteoarthritis diagnosed by photography (HOASCORE)BMC Musculoskeletal Disorders
Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locusHuman Molecular Genetics
Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritisNature Genetics

2016

Incidence and prevalence of total joint replacements due to osteoarthritis in the elderly: Risk factors and factors associated with late life prevalence in the AGES-Reykjavik StudyBMC Musculoskeletal Disorders

2015

Sex-specific predictors of hearing-aid use in older persons: The age, gene/environment susceptibility-Reykjavik studyInternational Journal of Audiology

2014

Reliability of assessing hand osteoarthritis on digital photographs and associations with radiographic and clinical findingsArthritis Care and Research
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hipAnnals of the Rheumatic Diseases
Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31Nature Genetics

2013

How to define responders in osteoarthritisCurrent Medical Research and Opinion
Type 3 finger length pattern is associated with total knee replacements due to osteoarthritis but not with hip replacements or hand osteoarthritis in the elderly: The AGES-Reykjavik studyBMC Musculoskeletal Disorders

2012

Identification of new susceptibility loci for osteoarthritis (arcOGEN): A genome-wide association studyThe Lancet
The use of digital photographs for the diagnosis of hand osteoarthritis: The AGES-Reykjavik studyBMC Musculoskeletal Disorders
Genetic predisposition of the severity of joint destruction in rheumatoid arthritis: A population-based studyAnnals of the Rheumatic Diseases

2011

Identification of low-frequency variants associated with gout and serum uric acid levelsNature Genetics
Hand osteoarthritis severity is associated with total knee joint replacements independently of BMI. The Ages-Reykjavik studyOpen Rheumatology Journal
Impact of cryopreservation on serum concentration of matrix metalloproteinases (MMP)-7, TIMP-1, vascular growth factors (VEGF) and VEGF-R2 in Biobank samplesClinical Chemistry and Laboratory Medicine
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN studyAnnals of the Rheumatic Diseases
A variant in MCF2L is associated with osteoarthritisAmerican Journal of Human Genetics
Large scale replication study of the association between hla class ii/btnl2 variants and osteoarthritis of the knee in european-descent populationsPLoS ONE
Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortiumOsteoarthritis and Cartilage
The presence of total knee or hip replacements due to osteoarthritis enhances the positive association between hand osteoarthritis and atherosclerosis in women: The AGES-Reykjavik studyAnnals of the Rheumatic Diseases
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22Annals of the Rheumatic Diseases

2010

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22Arthritis and Rheumatism
Erratum to A genome-wide association study identifies a common variant near the GPR22 gene as a new locus involved in prevalence and progression of osteoarthritis [Bone, 44S2 (2009) S224]Bone

2009

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and handArthritis and Rheumatism
Hand osteoarthritis in older women is associated with carotid and coronary atherosclerosis: The AGES Reykjavik studyAnnals of the Rheumatic Diseases
High hand joint mobility is associated with radiological CMC1 osteoarthritis: the AGES-Reykjavik studyOsteoarthritis and Cartilage

2006

Hand radiology characteristics of patients carrying the T303M mutation in the gene for matrilin-3Scandinavian Journal of Rheumatology

2003

Genomewide scan for hand osteoarthritis: A novel mutation in matrilin-3American Journal of Human Genetics
The inheritance of hand osteoarthritis in IcelandArthritis and Rheumatism

2001

The inheritance of rheumatoid arthritis in IcelandArthritis and Rheumatism
A large icelandic family with early osteoarthritis of the hip associated with a susceptibility locus on chromosome 16pArthritis and Rheumatism

2000

CPH 82 (Reumacon®) in refractory inflammatory arthritisScandinavian Journal of Rheumatology

1999

Scintigraphic hand osteoarthritis (OA) - Prevalence, joint distribution, and association with OA at other sitesJournal of Rheumatology
Articular hypermobility in Icelandic 12-year-oldsRheumatology

1998

More on Petursson and rheumatoid arthritis [2] (multiple letters)Scandinavian Journal of Rheumatology
Combined elevation of IgM and IgA rheumatoid factor has high diagnostic specificity for rheumatoid arthritisRheumatology International

1997

International letter Rheumatology in IcelandBritish Journal of Rheumatology
IgA rheumatoid factor correlates with changes in B and T lymphocyte subsets and disease manifestations in rheumatoid arthritisJournal of Rheumatology

1996

Hypermobility associated with osteoarthritis of the thumb base: A clinical and radiological subset of hand osteoarthritisAnnals of the Rheumatic Diseases
Hand Osteoarthritis in the Elderly: Application of Clinical CriteriaScandinavian Journal of Rheumatology
Rheumatoid arthritis in an Icelandic textbook from 1782Scandinavian Journal of Rheumatology

1995

Raised iga rheumatoid factor (RF) but not igm RF or igg RF is associated with extra-articular manifestations in rheumatoid arthritisScandinavian Journal of Rheumatology
Hypermobility features in patients with hand osteoarthritisOsteoarthritis and Cartilage
Prospective analysis of C1 dissociation and complement activation in patients with systemic lupus erythematosusClinical and Experimental Rheumatology

1993

Clustering of neutrophil leucocytes in serum: Possible role of C1q-containing immune complexesClinical and Experimental Immunology

1992

Evidence of rheumatoid arthritis in an icelandic textbook from 1782.Sydsvenska medicinhistoriska sallskapets arsskrift. Supplementum

1991

C1 subcomponent complexes and C2 cleavage in active systemic lupus erythematosusComplement and Inflammation

1990

Autoantibodies against neutrophil cytoplasm components in systemic lupus erythematosus and in hydralazine-induced lupusClinical and Experimental Immunology
A novel assay for neutrophil clustering activity of human sera: Relation to disease activity and neutropenia in systemic lupus erythematosusAnnals of the Rheumatic Diseases
Homozygous C4A deficiency in systemic lupus erythematosus: analysis of patients from a defined populationClinical Genetics
Estimating the incidence of systemic lupus erythematosus in a defined population using multiple sources of retrievalRheumatology
Recurrent cerebral infarction and the antiphospholipid syndrome: Effect of intravenous gammaglobulin in a patient with systemic lupus erythematosusAnnals of the Rheumatic Diseases

1989

CIRCULATING ANTI-ELASTASE IN SYSTEMIC LUPUS ERYTHEMATOSUSThe Lancet
Lung function in patients with systemic lupus erythematosus and persistent chest symptomsRheumatology
Outcome in systemic lupus erythematosus: a prospective study of patients from a defined population.Medicine
Outcome in systemic lupus erythematosus: A prospective study of patients from a defined populationMedicine (United States)
On systemic lupus erythematosus clinical studies with special reference to epidemiology, lung function and complement activationScandinavian Journal of Rheumatology
Anti-neutrophil cytoplasm antibody as a new serologic marker,Antineutrofil cytoplasma-antikropp ny serologisk markör.Lakartidningen

1988

Complement fixation by solid phase immune complexes. Reduced capacity in SLE seraJournal of Clinical and Laboratory Immunology
The effect of age on clinical and serological manifestations in unselected patients with systemic lupus erythematosusJournal of Rheumatology
Thyroid disorders are related to secondary sjögren's syndrome in unselected systemic lupus erythematosus patientsArthritis & Rheumatism

1987

Thyroid disorders in systemic lupus erythematosus are associated with secondary Sjögren's syndrome.Annals of the rheumatic diseases

1986

Symptomatic secondary Sjogren's syndrome in patients with systemic lupus erythematosus (SLE). Relation to anti-SS-A and anti-SS-B autoantibodiesScandinavian Journal of Rheumatology
No effect of acetylcysteine on refractory rheumatoid arthritisClinical and Experimental Rheumatology

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